Agenda and Technical Program
Tuesday May 31st
4:00 PM
Check-in opens
6:00 PM
Welcome & reception
Courtyard Lawn
6:30 PM
Colloquium - 40th Anniversary of the Vannucci Model
Courtyard Lawn
Chair: Donna Ferriero
6:30-7:00 Invited Speaker: Susan Vannucci (She/Her); Professor of Neuroscience, Department of Pediatrics, Brain and Mind Institute, Weill Cornell Medical College
"Hypoxia-Ischemia in the Neonatal Brain: 40 years of a preclinical model"
7:00-7:30 Invited Speaker: Hemmen Sabir (He/Him); Professor and Doctor of Neonatal Neuroscience; German Center for Neurodegenerative Diseases (DZNE)
"Present and Future of the Vannucci Rat model of Hypoxia-Ischemia"
Wednesday June 1st
7:00 AM
Breakfast
MNT WA - BC
8:30 AM
Session 1: Long term consequences of developmental brain injury
Olympic Ballroom
Chairs: Sunny Juul and Sarah Kolnik
8:30-9:15 Keynote Speaker: Steve Miller (He/him); Hudson Family Hospital Chair in Pediatric Medicine, Professor and Head, Department of Pediatrics, Faculty of Medicine, University of British Columbia
"Brain Health in the Neonate: from connectome to home"
9:15-9:30 Break
9:30-10:00 Invited Speaker: Marie-Eve Tremblay (She/Her); Associate Professor, Canada Research Chair (Tier II) of Neurobiology of Aging and Cognition, Division of Medical Sciences, University of Victoria
"Microglial ultrastructural diversity providing novel targets for intervention"
10:00-10:30 Invited Speaker: Tommy Wood (He/Him), Research Assistant Professor of Pediatrics, Director of Preclinical Research, Division of Neonatology, Department of Pediatrics
“Can we prevent the adverse neurological outcomes of adults born preterm?”
10:30-10:45 Break
10:45 AM
Session 1 & 2: Oral Abstract Presentations
Olympic Ballroom
Chairs: Sunny Juul and Sarah Kolnik
10:45-11:00 Jessica Wisnowski, Children’s Hospital Los Angeles, University of Southern California;
"The Effect of Erythropoietin on Brain Injury in Neonates with Hypoxic-Ischemic Encephalopathy: Neuroimaging Outcomes in the HEAL Trial"
11:00-11:15 Henrik Hagberg, Centre of Perinatal Medicine & Health, Sahlgrenska Academy, Gothenburg University;
"Repurpose of Exendin-4 for the treatment of preterm and term neonatal brain injury"
11:15-11:30 Kengo Onda, Johns Hopkins University School of Medicine;
"Development of a Diffusion Tensor Imaging Composite Score for Prediction of Short-Term Neurological Outcome in Neonatal Hypoxic-Ischemic Encephalopathy"
11:30-11:45 Panagiotis Kratimenos, Department of Pediatrics, Division of Neonatology, Children’s National Hospital, George Washington University School of Medicine;
"Cellular and Molecular Alterations of Human Cerebellum in Sudden Infant Death Syndrome"
11:45-12:00 Howard Chao, Baylor College School of Medicine;
"Comparison of near-infrared spectroscopy based cerebral autoregulatory indices in extremely low birth weight infants"
12:00 PM
Lunch
3 Faculty-Led Mentoring Tables
Courtyard Lawn
1:30 PM
Session 2: Brain aging and susceptibility to second hit events
Olympic Ballroom
Chairs: Tommy Wood and Frances Northington
1:30-2:15 Keynote Speaker: Matt Kaeberlein (He/Him), Professor of Laboratory Medicine and Pathology, Director, Healthy Aging and Longevity Research Institute; Director, Nathan Shock Center for Excellent in the Basic Biology of Aging, University of Washington
"Targeting biological aging: A new paradigm for 21st century medicine"
2:15-2:30 Break
2:30-3:00 Invited Speaker: Raul Chavez-Valdez (He/Him), Associate Professor of Pediatrics, Johns Hopkins School of Medicine
"Long-term GABAergic and cholinergic disruption after developmental brain injury."
3:00-3:30 Invited Speaker: Pauly DiTuro (He/Him), Columbia Innovation Center at the University of South Carolina, Founder and Performance Director, BrainStorm Lab
"Left of Bang"
3:30 PM
Poster Presentations - odd numbers
MNT WA - BC
Session ends at 5:30pm
6:30 PM
Dinner
Olympic Ballroom
Thursday June 2nd
7:00 AM
Breakfast
MNT WA - BC
8:30 AM
Session 3: Epigenetics and microbiome effects
Olympic Ballroom
Chairs: Henrik Hagberg and Hemmen Sabir
8:30-9:15 Keynote Speaker: Carina Mallard (She/her), Deputy Vice Chancellor and Professor, Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg
"Short- and long-term effects of neonatal inflammation on the brain and behaviour."
9:15-9:30 Break
9:30-10:00 Invited Speaker: Greg Valentine, Assistant Professor, Department of Pediatrics, Division of Neonatology, University of Washington
"The relationship between the perinatal microbiome and offspring brain development."
10:00-10:30 Invited Speaker: Staci Bilbo (She/her), Professor, departments of Psychology and Neuroscience, Neurobiology, and Cell Biology, Duke University
"Prenatal inflammation in response to environmental stressors."
10:30-10:45 Break
10:45 AM
Session 3 & 4 Oral Abstract Presentations
Olympic Ballroom
Chairs: Henrik Hagberg and Hemmen Sabir
10:45-11:00 Olivia White, University of Washington
"Rectal temperature 1h after inflammation-sensitized hypoxia-ischemia predicts long-term white matter and cortical pathology in the late preterm ferret"
11:00-11:15 Lee Martin, Professor of Pathology, Division of Neuropathology, Professor of Neuroscience, Anesthesiology & Critical Care Medicine, Johns Hopkins University School of Medicine
"Calretinin and Parvalbumin Trapping of TDP-43 and XRCC1 May Drive Neocortical Interneuron Death in Neonatal Piglet and Human Hypoxic-Ischemic Encephalopathy"
11:15-11:30 Adrian Epstein, Duke University
"Inflammatory Injury in the Postnatal Subventricular Zone Neural Stem Cell Niche Follows Neonatal Intestinal Perforation"
11:30-11:45 Sarah Hamimi, Johns Hopkins University School of Medicine
"PNN Degradation and Loss of OTX2 in Adult Rats with Cerebral Palsy and an Adult-onset Chronic Pain Phenotype"
12:00 PM
Lunch
3 Faculty-Led Mentoring Tables
Courtyard Lawn
1:30 PM
Session 4: Mechanisms and cellular imaging
Olympic Ballroom
Chairs: Jessica Wisnowski and Lauren Jantzie
1:30-2:15 Keynote Speaker: Juliette Van Steenwinckel (She/Her), Director, PROTECT Lab, INSERM
"Systemic Inflammation and neurodevelopmental disorders: an unprivileged brain"
2:15-2:45 Invited Speaker: Vanessa Coelho Santos (She/Her), Postdoctoral Fellow, Department of Pediatrics, University of Washington
"Imaging the development of brain microvascular architecture: normoxia vs hypoxia"
2:45-3:00 Break
3:00-3:30 Invited Speaker: David Menassa (He/Him), Stipendiary Lecturer of Neurophysiology & Neuroscience, The Queen's College, University of Oxford
"Spatiotemporal Dynamics of Microglia Across the Human Lifespan"
3:30-4:00 Invited Speaker: Elizabeth Nance (She/Her), Associate Professor of Chemical Engineering, Bioengineering, Center on Human Development and Disability, eScience Institute; Associated Chair of Undergraduate Studies, Department of Chemical Engineering, University of Washington
"Imaging cellular and extracellular stimuli-dependent changes in the brain microenvironment"
4:00 PM
Poster Presentations - even numbers
Session ends at 6:00pm
MNT WA - BC
6:30 PM
Dinner
After Dinner Party & Dancing
Olympic Ballroom
Friday June 3rd
7:00 AM
Breakfast
MNT WA - BC
8:30 AM
Session 5: Societal, environmental, and systemic effects on premature/low-birth weight infants
Olympic Ballroom
Chairs: Steven Miller and Elizabeth Nance
8:30-9:15 Keynote Speaker: Nana Matoba (She/Her), Associate Professor of Pediatrics, Prentice Women’s Hospital and Lurie Children’s Hospital, Northwestern University Feinberg School of Medicine
"Racism and Adverse Birth Outcomes"
9:15-9:45 Invited Speaker: Krystle Perez (She/Her), Assistant Professor, Department of Pediatrics, Division of Neonatology, Department of Global Health, University of Washington
"Nature, Nurture, Neighborhood and Beyond: Inclusive Strategies for Optimizing Newborn Outcomes."
9:45-10:00 Break
10:00-10:30 Invited Speaker: Claudia Lugo-Candelas (She/Her), Assistant Professor, Clinical Medical Psychology, Department of Psychiatry, Columbia University
"Perinatal sleep health disparities: intergenerational legacies on offspring brain development"
10:30-11:00 Invited Speaker: Jaime Slaughter-Acey, Assistant Professor, Division of Epidemiology and Community Health, University of Minnesota
11:00-11:15 Break
11:15 AM
Session 5 Oral Abstract Presentations
Olympic Ballroom
Chairs: Steven Miller and Elizabeth Nance
11:15-11:30 Agnes Chao, Duke University Medical Center
"Breast milk-associated oxysterol reverses neonatal white matter injury through Gli2-dependent oligodendrogenesis"
11:30-11:45 Thiviya Selvanathan, The Hospital for Sick Children
"Early-life exposure to analgesic medications and neurodevelopmental outcomes in very preterm neonates"
11:45-12:00 Josephine Herz, University Hospital Essen
"Regulatory T cells contribute to sexual dimorphism in neonatal hypoxic-ischemic brain injury"
12:00-12:15 Lauren Jantzie, Johns Hopkins University School of Medicine
"Perinatal Exposure to Cyclohexanone Induces Structural and Functional Brain Injury"
12:15 PM
Meeting Wrap-up & Hershey 2024
Chairs: Sunny Juul and Donna Ferriero
12:30 PM
Meeting Adjourn & Box Lunch
Olympic Ballroom